As early as 1920s, There was a Catholic Community in Tai O, and a small church building was raised at this location around 1923 but it was not designated as a church. The building was then destroyed by typhoon. After being redeveloped in 1937, it was designated as a church and named Our Lady of Perpetual Help Chapel, belonging to the Fatima Parish of Cheung Chau. Rev. BRUZZONE, Edmondo PIME (潘崇理神父) served as its pastor till 1941.
On 11 June,1962, the new church building in Tai O was blessed and Fr. Nicola Ruggiero PIME was the rector of the Chapel. In 1965, Tai O Church and Cheung Chau Church were separately designated as independent Districts and on 1 July 1979 the Perpetual Help Chapel was erected as an independent parish. The priests residing in Tai O also took care of it’s Mass Centre in Mui Wo. It was then put under the purview of Epiphany Parish of Mui Wo on 8 September 1980.
Other than the missionaries from the Pontifical Institute for Foreign Missions (PIME), the Catholic Community in Lantau was also served by the priests from the Oblates of Mary Immaculate (OMI), the Divine Word Missionaries (SVD).
Since 1 November 2015, Claretian Missionary priests undertake the pastoral care of the Catholic Community in Tai O. Holy Eucharist is celebrated in Cantonese in the Chapel at 10 am on every Saturday and there is also a weekly gathering for Bible Sharing on every Tuesday.